Yes, by an advanced technology called ICSI (Intra-cytoplasmic sperm injection), if the sperms are mature and healthy, they can be retrieved by natural or artificial means and can be injected into the oocyte in order to fertilize them. In such cases it is advisable that husband undergoes certain tests (Karyotyping and microdeletion test) beforehand to find out that he is not carrying a genetic defect which could be passed on to his son.