Our IVF Story
Being the pioneers of Infertility treatment in Karnal, we started the services in 1995. We first started with IUI and later moved on to IVF in 2010. Since then, we have handled over 10,000 cases of infertility and successfully helped deliver over 1000 babies at our premises. Our success rate in IVF is 40%, which is at par with the worldwide industry standards.
About Amrit IVF
Amrit fertility Clinic has been dedicated to the treatment of infertile couples for the last 20 years now and so far we have “produced” about 2000 babies as a result of various treatments that we offer. Our first IUI baby was born more than 20 years back. We have improved since then, added more facilities, kept abreast with newer technologies, and our ART results today are as good as any of the best centres in India.
Amrit IVF Centre, to provide the facility of IVF and other advanced ARTs was started in Jan 2010. Though a very new centre, it has given excellent results, an unbelievable 100% pregnancy in its very first batch. This goes to show the excellent quality of our Lab & equipment (from Trivector India, the leaders in IVF technology) and also the complete dedication & commitment of our team to give best possible results in our patients of Infertility. Soon after, the facility of ICSI was added on in order to meet the need of many patients for this service. A state of art micromanipulator from Nikon was installed in July 2010. very soon after that, we realised the need of cryopreservation, and the facilities of vitrification also.
Techniques
What is Assisted Reproductive Technology (ART)?
Any medical technique that attempts to obtain a pregnancy by means other than by intercourse is defined as Assisted Reproductive Technology. The various methods are:
Intra Uterine Insemination (IUI):
IUI or AIH (Artificial Insemination Husband) is the first line of treatment in Infertility and can be used to treat both male and female factor infertility. In this method, the processed semen is placed directly in the uterus, thereby increasing the chances of pregnancy. IUI can be done in a natural cycle, however to get better results, it is usually preceded by ovulation induction/Ovarian stimulation using appropriate fertility enhancing drugs. Its main indications are poor sperm count in males, anatomical defects in females and unexplained infertility. This procedure is useful only when one of the fallopian tubes is patent and the woman has a minimal ovarian reserve.
This process is also used for using donor sperms, when its called AID (Artificial Insemination Donor), when the male partener has total azoospermia or severe Oligozzospermia, which is not treatable and ICSI is not possible/affordable.
In Vitro Fertilization (IVF) and Embryo Transfer (ET):
Commonly know n as ‘Test Tube Baby’ IVF involves fertilization of an ovum outside the body and consequently transfer of the fertilized ovum (embryo) into the uterus of the woman. IVF is probably the most widely practiced assisted conception procedure in the world. It is totally an OPD procedure and does not need admission at any step. Its main indications are:
- Blocked Fallopian Tubes
- Poor Sperm Count (Oligo or Asthenozoospermia <5million/ml)
- Endometriosis
- Unexplained Infertility
- Premature Ovarian failure
- Genetic disease in the couple’s family
Steps involved in IVF Procedure:
FIRST VISIT- Counselling of the couple regarding the procedure,the best treament suitable for them, the protocols and their chances of success.
PRELIMINARY INVESTIGATIONS- Blood tests, X-ray, ECG, Hormone tests, Ultrasound, Hysteroscopy and Semen tests.
Final PROCESS OF IVF:
- Ovarian stimulation by hormonal injections to produce multiple eggs
- Monitoring of the response by ultrasound scans and blood tests
- Egg retrieval with the help of a needle under local/general anesthesia
- Fertilization of the eggs in laboratory
- Transfer of the resulting embryo(s) into the uterus of the woman
Blood test performed 15 days after embryo transfer, to assess the establishment of pregnancy. If the treatment procedure is successful, one or more of the embryos will implant in the uterus and pregnancy will result, just as it happens in the natural process of conception.
Intra Cytoplasmic Sperm Injection (ICSI):
ICSI is the technological breakthrough in the field of IVF, which is used to overcome the inability of sperm to fertilize an egg. Its main indications include male factors like severe oligozoospermia, so but can also used in repeated IVF Failure. In this technique a sperm is directly injected into the cytoplasm of an egg in order to achieve fertilization. The steps involved in ICSI procedure are exactly the same as for IVF, except that fertilization is achieved with the help of a micromanipulator. In some cases where there is a complete absence of sperm in the ejaculate, sperm can be retrieved from the testis / epididymis and used for ICSI. The testicular/epididymal sperm retrieval techniques are: PESA (Percutaneous Epididymal Sperm Aspiration), MESA (Microsurgical Epididymal Sperm Aspiration), TESA (Testicular Sperm Aspiration), TESE ((Testicular Sperm Extraction)
IVF using Donor Oocyte (Eggs):
Women who are unable to produce their own eggs or whose eggs fail to fertilize during an IVF cycle due to poor Oocyte quality, can be helped by using other women’s eggs (Donor Oocyte). The resulting embryo is then transferred to mother’s womb. This allows the woman to bear her husband’s child and also experience the joys of motherhood. The eggs may be obtained either from a professional donor (from ART banks) or by using the egg sharing program.
EMBRYO DONATION; It is the replacement of donor embryos in the uterus of the wife of desirous couple, when both of them are suffering from poor eggs and sperm count.
SURROGACY: When the uterus of the woman is unable to carry the pregnancy till term because of reasons like infections, malformations, multiple myomas or absence or surgical removal of the uterus, we can offfer the option of Surrogacy to such couples. The surrogates are provided by the ART Banks which also deal with the legal aspect of surrogacy.
Assisted Hatching:
This procedure is based on the fact that an alternation in the zona pellucida (outer covering of the egg) either by drilling a hole through it or by thinning it, will promote hatching or implantation of embryos that are otherwise unable to escape intact from the zona pellucida.
Cryo Preservation of Embryos (Vitrification):
Excess (Surplus) Embryos can be cryo-preserved at ultra low temperatures for many years. These frozen embryos can be used subsequently without the need for ovarian stimulation and egg retrieval. As of today, the pregnancy rate after transfer of frozen embryos is as good as with fresh embryos. In fact, it’s better in certain circumstances like OHSS when the hormonal profile becomes disturbed due to formation of a large number of eggs. Also when the uterine lining is not very favourable, or if the embryos cannot be transferred because of any reason, they can be vitrified and stored for a later use.
Semen / Sperm Freezing:
Semen/ Sperm or testicular biopsies can be stored frozen at ultra low temperatures for a long duration for future use or analysis. Semen Bank: Amrit IVF Centre has facility for storage of semen samples, for its own patients for future use. We also keep frozen sperm samples obtained from certified sperm banks in New Delhi, with various backgrounds and physical characteristics to match individual needs. Donors are screened thoroughly to rule out any transmission of infectious or genetic diseases.
Risks Involved in ARTs
1. Multiple pregnancy
2. Ovarian Hyperstimulation Syndrome (OHSS)
3. Failure at different steps of IVF Treatment
4. Ectopic pregnancy
5. The incidence of congenital malformation in IVF babies is no more than in the general population.
Success Rate: Apart from the expertise of the individual fertility clinic there are other factors, which affect the ART outcome, such as patient’s age and the variety of abnormalities, causing infertility. Some of these abnormalities respond well to IVF while others do not. This means that some patient will have a good chance of pregnancy while others will have a poor chance. A good Lab normally has a 30 – 40 % pregnancy rate per attempt.
Our USP is the low cost at which we provide this treatment, probably lower than anywhere else in India.
Other Treatment Options Available:
Laparoscopy & Hysteroscopy: There are various conditions which require surgical treatments eg Congenital defects in the uterus or cervix, myomas, Polyps, Tubal Blockage, Hydrosalpinx, Ovarian drilling for Polycystic ovaries, ashermann’s syndrome etc. Both Diagnostic and Therapeutic laparoscopy and hysteroscopy are hysteroscopic surgeries are done by fully experienecd team of laparoscopic surgeons.
You are welcome to visit our centre at any time convenient to you..